Adam Dunn and Paul Konerko each hit two-run homers and the Chicago White Sox spoiled the debut of Oakland interim manager Bob Melvin, beating the Athletics 9-4 on Thursday night.
Melvin replaced Bob Geren earlier in the day, but the change couldn't keep Oakland from its 10th straight defeat.
Mark Buehrle (6-4) threw seven strong innings and improved to 5-1 with a 3.00 ERA in his last seven starts. He allowed seven hits and three runs for the White Sox, who have won six of their last nine and 20 of 32.
Dunn was back in the lineup after sitting out two games because of a miserable start in which he has hit . 176. He was hit by a pitch and scored in Chicago's three-run second. He homered for the first time since May 24, a two-run shot in the third.
Trevor Cahill (6-4) lasted just 2 2-3 innings, his shortest outing of the season. He was unlucky to an extent, allowing four infield hits on dribblers in front of the plate. But he also walked three, hit a batter and allowed Dunn's two-run blast.
It was a rocky introduction for Melvin, who went 493-508 in previous managerial stops in Seattle and Arizona. The Athletics, who entered last in the AL with 223 runs scored, scored three runs or less for the fifth straight game, and eighth time during their skid. Oakland last lost 10 straight from July 28-Aug. 7, 2008.
In the second, the White Sox loaded the bases on A.J. Pierzynski's walk, Alex Rios' single and Dunn's hit by pitch. After Oakland third baseman Adam Rosales dropped a foul pop, Omar Vizquel hit a sacrifice fly to right to plate Chicago's first run.
Gordon Beckham reached on a tapper in front of the plate, reloading the bases. Juan Pierre walked in a run, and then Alexei Ramirez hit a dribbler up the third-base line that Cahill was unable to handle, scoring the inning's third run.
As maddening as that inning was for Cahill, the third was more of the same _ at least after Dunn's two-run shot to barely cleared the left-field fence for his sixth homer of the year.
Vizquel followed that with another short dribbler to reach first. Beckham singled and Pierre reached on yet another infield hit to load the bases. Ramirez drew a walk to score Vizquel, a fitting end to a frustrating night for Cahill, who gave way to reliever Bobby Cramer.
Cahill is now 0-4 in his last six starts.
Meanwhile, Buehrle allowed Rosales' run-scoring single in the second, the last of three straight singles for Oakland. He then settled down to throw 4 2-3 scoreless innings, allowing only a walk and an infield single in the third.
Buehrle ran into trouble in the seventh when Kurt Suzuki hit a leadoff single and Hideki Matsui hit his fourth homer of the season, cutting Chicago's lead to 6-3.
The White Sox tacked on three runs in the eighth on Carlos Quentin's sacrifice fly and Konerko's two-run blast, all off Oakland reliever Brian Fuentes.
Oakland rookie Jemile Weeks drove in his first career run on a bloop single in the ninth.