Carlos Carrasco was chased in the fourth inning, Lonnie Chisenhall misplayed two balls in right field and Roberto Perez's passed ball cost Cleveland a run.

It was that kind of night for the Indians.

"That's about as bad of a game as we've played in a while," manager Terry Francona said.

Mike Napoli connected for his 33rd homer, but that was one of the only highlights for the Indians in an 11-4 loss to the Chicago White Sox on Monday night. Chicago scored in every inning for the first time since a 12-8 victory over the Boston Red Sox on May 11, 1949, according to STATS.

"It's a tough way to start a series," Chisenhall said. "Offense and defense both weren't going at the same time. Fortunately, it's a four-game series and we can still win it."

Cleveland's lead in the AL Central was trimmed to six games over Detroit, which rallied for a 4-2 victory over Minnesota. The Indians had won eight of their last nine against the White Sox.

Carrasco (11-8) allowed four runs and eight hits in 3 2/3 innings, hours after the Indians announced All-Star starter Danny Salazar could miss the rest of the season with a forearm injury.

"Those guys came in very aggressive and hit everything," Carrasco said. "You just move on and tomorrow is another day."

Salazar had an MRI in Cleveland and was diagnosed with a mild strain to his flexor musculature. The right-hander, a key part of the Indians' rotation, will be sidelined for three to four weeks, leaving open the possibility he could return in some capacity for the playoffs.

"The one thing we want to do is get him healthy, make sure he knows he's healthy, because that's important," Francona said, "and then if it fits somewhere, good. But the biggest thing is to get him healthy."

Todd Frazier, Avisail Garcia and Adam Eaton homered as the White Sox improved to 4-3 on their 10-game homestand. Tim Anderson had three of Chicago's 16 hits and Jose Abreu drove in two runs, backing another strong start by Miguel Gonzalez (4-6).

"We swung the bats tonight," manager Robin Ventura said. "All the way through the lineup everybody seemed to be clicking."

Gonzalez allowed three runs and six hits over 6 2/3 innings in his second straight win since coming off the disabled list after being sidelined by a strained right groin. He pitched 6 1/3 innings in a 2-0 victory over Detroit last Tuesday.

TRAINER'S ROOM

Indians: C Yan Gomes (separated right shoulder) is expected to catch nine innings for Double-A Akron on Tuesday night and then serve as the designated hitter Wednesday. "Then we'll kind of re-evaluate what's going on after that," Francona said.

White Sox: Abreu was shaken up when he was accidentally hit in the face by Jason Kipnis while applying a tag in the third inning. It also looked as if something was bothering Abreu after a hard slide back into first in the fifth, but he stayed in the game. "He'll probably feel it tomorrow," Ventura said.

UP NEXT

Indians RHP Trevor Bauer and White Sox LHP Jose Quintana get the ball Tuesday night. Bauer (11-6, 3.86 ERA) is looking for his third consecutive victory and career-best 12th on the season. Quintana (11-10, 3.13 ERA) is winless in two September outings, but 5-3 with a 2.70 ERA in 15 career starts against the Indians.