Ivan Nova pitched eight scoreless innings, and the Chicago White Sox beat the Detroit Tigers 8-1 on Wednesday.
Nova (7-9) allowed five hits, walked three and struck out one as he picked up his third win in four starts.
Former Tiger James McCann had three RBIs, while Tim Anderson reached base five times and scored three runs.
The White Sox took three of four games from the Tigers and went 5-2 on their trip to Philadelphia and Detroit.
Detroit has lost six of seven and is 5-21 since the All-Star break.
Tyler Alexander (0-3) allowed five runs on nine hits and a walk in 4 1/3 innings.
First baseman Brandon Dixon pitched a scoreless ninth for the Tigers. He has a 5.40 ERA in four pitching appearances over the past two seasons.
McCann had an RBI double in the first, and Ryan Cordell made it 2-0 with a long homer in the second.
Detroit loaded the bases with one out in the second, but Nova got Jody Mercer to ground into a double play.
Wellington Castillo had an RBI double in the third, and the White Sox added on in the fifth. Anderson led off with his third hit of the game and scored his third run on José Abreu's double. McCann added an RBI single to make it 5-0 and end Alexander's day.
Abreu's single off Eduardo Jiménez in the sixth gave the White Sox a 6-0 lead, and Chicago added two more in the eighth. Travis Demeritte provided Detroit's only run with a two-out RBI triple in the ninth.