Illinois State Police responded to three semi trucks involved in an accident on the eastbound lanes of the Eisenhower Expressway at St. Charles Road.
Police say shortly before 11a.m. Sunday, both trucks were traveling in the center right lane. For unknown reasons, one truck lost control and struck the rear of the other truck, which hit the third truck.
Two trucks became engulfed in flames upon impact, according to Illinois State Police.
One of the drivers, a 39-year-old man, was transported to a local hospital with life threatening injuries.
All westbound lanes along I-290 are open. The eastbound lanes of I-290 will likely remain closed for several hours as the investigation continues.
Illinois State Police are investigating.