He drove to the hoop, went up for the shot, and then in a second, came crashing down.
"I'm kind of banged up right now, but this is basketball," Rose told ChicagoBulls.com while in the locker room after the game. "(I thought) I hope anything isn't broke. If everything is just sore, I can play through it, but playing with something that's broke or fractured is something totally different."
Rose also injured his ankle during the game.
Team doctors plan to re-evaluate his injuries on Tuesday.
Derrick Rose leads the Bulls with an average 24.7 points per game. He's fourth overall in the NBA for points scored.
The team heads to Toronto on Wednesday. They host the L.A. Clippers at the United Center on Saturday.