Paul Konerko and Alex Rios hit back-to-back homers and Alejandro De Aza added a grand slam to cap a six-run sixth, leading the Chicago White Sox to an 11-8 victory over the Minnesota Twins on Thursday night.
A.J. Pierzynski and Dayan Viciedo also went deep as the White Sox won for the sixth time in seven games.
Konerko had two hits and drove in two runs. Rios also had two hits and knocked in three, and Chicago pulled this one out even though Philip Humber couldn't protect an early 4-1 lead.
The Twins knocked him out during a four-run fifth, sending 10 batters to the plate. Joe Mauer homered in the inning and Brian Dozier capped the rally with a two-run single to give Minnesota a 5-4 lead, but the debuting Cole De Vries couldn't hold it.
Konerko and Rios chased him with back-to-back homers to left leading off the sixth, putting Chicago back on top, and the White Sox kept pouring it on from there.
They loaded the bases with one out against Brian Duensing before De Aza, who had an earlier homer wiped out by instant replay, drove a 1-0 pitch over the right-field bullpen to make it 10-5. The grand slam was the first of his career and the first by the White Sox since Rios hit one against Cleveland on Sept. 10, 2011.
The big rally made a winner of Nate Jones (2-0), who allowed two hits over 1 2-3 innings. He came in for Humber in the fifth and immediately gave up that two-run single by Dozier, but the White Sox came out on top, anyway.
They had their way with De Vries (0-1), who grew up near Minneapolis and played for the University of Minnesota. The 27-year-old right-hander gave up six runs — three earned — and six hits.
He was shaky right from the start. Pierzynski drove a solo homer off the right-field pole in the second and the White Sox added to their lead in the third after Alexi Casilla booted De Aza's grounder to second with one out. Konerko extended his hitting streak to 10 with an RBI single, and Rios added a two-run double to make it 4-1.
Humber still hasn't won since his perfect game against Seattle on April 21 and the right-hander is 0-2 in his last six starts after allowing five runs and six hits in 4 1-3 innings.
Justin Morneau hit two late homers for Minnesota — a leadoff homer against Will Ohman in the seventh and a two-run drive against Addison Reed in the ninth.