Chris Coghlan hit a leadoff homer in the first and Javier Baez had his second career three-hit game, leading the Chicago Cubs to a 6-4 victory over the Milwaukee Brewers on Friday night.

The Brewers lost for the 24th time in 34 games on a day the team said it would retire uniform No. 1 to honor retiring Commissioner Bud Selig, who bought the Seattle Pilots out of bankruptcy and moved them to Milwaukee in 1970.

Coghlan homered on Jimmy Nelson's second pitch of the game. He also doubled in the third and scored three times.

Neil Ramirez (3-3) pitched a perfect inning for the win and Hector Rondon got three outs for his 28th save in 32 chances.

Milwaukee went 2 for 18 with runners in scoring position and left 11 men on base. Jean Segura went 3 for 4 with his fifth homer.

Nelson (2-9) was charged with five runs and six hits in 4 1-3 innings.

Eric Jokisch pitched four innings for Chicago in his first major league start. He allowed two runs, one earned, and three hits while throwing 86 pitches.

Cubs manager Rick Renteria was ejected in the eighth inning for arguing with second base umpire Jeff Nelson.

Baez singled in each of his first three plate appearances and drove in two runs. It was his second three-hit performance in 50 games since joining the team on Aug. 5. He also had three hits, including two home runs, in his third game on Aug. 7.

Nelson was sent to the bullpen in early September but was starting for Matt Garza, who was shut down due to shoulder tightness. The right-hander struck out four and walked one.

Nelson was regarded as the Brewers' No. 1 pitching prospect coming into the season. In 14 appearances, including 12 starts, he had a 4.93 ERA. The team only won four of the 12 games he started.

The Cubs grabbed the lead for good with two runs in the third inning. Baez singled in Coghlan and then scored on a groundout by rookie Jorge Soler to give Chicago a 3-1 advantage.