Jennifer Aniston's next film, "The Baster," follows a woman who opts for artificial insemination – but would Jen herself go that route for kids?
But the 40-year-old single star admitted it wouldn't be her method of choice.
"It would not be my first choice," she told Billy.
And while children may still be a ways off for Jen, she's got no shortage of movies on the way – her latest, "Love Happens," opens on Friday.
Between films, the fit star is always in shape – so how does she do it?
"I actually Fred Flintstoned my way over here," she said, referencing the cartoon character's foot-powered car.
"That's really the whole trick so you can't give that away," Jen joked about her impressive legs.
But humor aside, she added it's an important part of her routine.
"I do love to run," she said.